BDBM50126147 CHEMBL3629571

SMILES c1cc(c(cc1C(=O)[C@H]2C[C@@H]2C(=O)O)Cl)Cl

InChI Key InChIKey=ZBRKMOHDGFGXLN-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50126147   

TargetKynurenine 3-monooxygenase(Human)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126147(CHEMBL3629571)
Affinity DataIC50: 20nMAssay Description:Inhibition of human KMOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Baker's yeast)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126147(CHEMBL3629571)
Affinity DataIC50: 74nMAssay Description:Inhibition of yeast KMOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKynurenine 3-monooxygenase(Rat)
Tes Pharma

Curated by ChEMBL
LigandPNGBDBM50126147(CHEMBL3629571)
Affinity DataIC50: 20nMAssay Description:Inhibition of rat liver KMO using [3,5-3H]-kynurenine substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126147(CHEMBL3629571)
Affinity DataIC50: 40nMAssay Description:Inhibition of KMO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed