BDBM50126113 CHEMBL3627749

SMILES CC(C)(C)OC(=O)Nc1ccc(cc1)-c1cn(CCC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(O)=O)nn1

InChI Key InChIKey=WSTXXFRRXUUZFV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126113   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50126113(CHEMBL3627749)
Affinity DataIC50: 5.74E+4nMAssay Description:Inhibition of human MDM2 (17 to 125 residues) assessed as reduction in MDM2 interaction with FAM-LTFEHYWAQLTS-CONH2 peptide incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50126113(CHEMBL3627749)
Affinity DataKi:  7.22E+3nMAssay Description:Inhibition of human MDM2 (17 to 125 residues) assessed as apparent inhibition constant for reduction in MDM2 interaction with FAM-LTFEHYWAQLTS-CONH2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed