BDBM50126086 CHEMBL24892::MT-II cyclic peptide derivative

SMILES CCCCC(=O)N[C@@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2cnc[nH]2)NC1=O)C(N)=O

InChI Key InChIKey=NMAOMCVHZQOUKD-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50126086   

TargetMelanocortin receptor 3(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126086(MT-II cyclic peptide derivative | CHEMBL24892)
Affinity DataEC50:  6nMAssay Description:Agonistic activity against human melanocortin receptor (hMC3R) for cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126086(MT-II cyclic peptide derivative | CHEMBL24892)
Affinity DataEC50:  33nMAssay Description:Agonistic activity against human melanocortin receptor (hMC5R) for cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126086(MT-II cyclic peptide derivative | CHEMBL24892)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human melanocortin receptor (hMC1R).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126086(MT-II cyclic peptide derivative | CHEMBL24892)
Affinity DataEC50:  0.900nMAssay Description:Agonistic activity against human melanocortin receptor (hMC1R) for cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed