BDBM50126085 CHEMBL384036::MT-II cyclic peptide derivative

SMILES CCCCC(=O)N[C@@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCNC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)C2(CCc3c(Cl)cccc3C2)NC1=O)C(N)=O

InChI Key InChIKey=PIYXFYPHLODUHH-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50126085   

TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126085(MT-II cyclic peptide derivative | CHEMBL384036)
Affinity DataIC50: 1.47E+4nMAssay Description:Binding affinity towards human melanocortin receptor (hMC1R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126085(MT-II cyclic peptide derivative | CHEMBL384036)
Affinity DataIC50: 675nMAssay Description:Binding affinity towards human melanocortin receptor (hMC4R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126085(MT-II cyclic peptide derivative | CHEMBL384036)
Affinity DataIC50: 675nMAssay Description:Binding affinity towards human melanocortin receptor (hMC4R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126085(MT-II cyclic peptide derivative | CHEMBL384036)
Affinity DataEC50:  105nMAssay Description:Agonistic activity against human melanocortin receptor (hMC4R) for cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126085(MT-II cyclic peptide derivative | CHEMBL384036)
Affinity DataEC50:  105nMAssay Description:Agonistic activity against human melanocortin receptor (hMC4R) for cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50126085(MT-II cyclic peptide derivative | CHEMBL384036)
Affinity DataIC50: 1.48E+4nMAssay Description:Binding affinity towards human melanocortin receptor (hMC1R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed