BDBM50125996 (R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(2-carbamoyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL280178

SMILES Cc1cccc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCC(N)=O

InChI Key InChIKey=GKYITRXFIIFDSO-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50125996   

TargetMu-type opioid receptor(Guinea pig)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125996((R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataIC50: 9.90nMAssay Description:Ability to inhibit electrically induced contractions of guinea pig ileum having mu opioid receptors tested in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125996((R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataIC50: 188nMAssay Description:Ability to inhibit electrically induced contractions of mouse vas deferens having delta opioid receptors tested in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125996((R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataKi:  0.0623nMAssay Description:Ability to displace [3H]DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125996((R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propion...)
Affinity DataKi:  2.57E+3nMAssay Description:Ability to displace [3H]-deltorphin II from delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed