BDBM50125944 CHEMBL3627832

SMILES Clc1ccc2c(c1)sc1c(nc3ccccc3c1c2=O)N1CCNCC1

InChI Key InChIKey=FNEFMBLKZVMMCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125944   

TargetDNA topoisomerase 2-alpha(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50125944(CHEMBL3627832)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant topoisomerase 2 alpha assessed as blocking of supercoiled pHOT DNA relaxation incubated for 45 mins at 37 degC by eth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50125944(CHEMBL3627832)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant topoisomerase 1 assessed as blocking of supercoiled pHOT DNA relaxation incubated for 25 mins at 37 degC by ethidium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed