BDBM50125905 (3R,4S)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-piperidin-3-ol::CHEMBL20127

SMILES O[C@H]1CN(Cc2ccc(F)cc2)CC[C@H]1CCOC(c1ccccc1)c1ccccc1

InChI Key InChIKey=SEGLRXUOVKIQDG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50125905   

TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50125905((3R,4S)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...)
Affinity DataIC50: 3.31E+3nMAssay Description:Binding affinity towards serotonin transporter in rat striatum using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50125905((3R,4S)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...)
Affinity DataIC50: 2.15E+3nMAssay Description:Binding affinity towards norepinephrine transporter in rat striatum using [3H]nisoxetine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50125905((3R,4S)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...)
Affinity DataIC50: 10.1nMAssay Description:Inhibition of uptake from dopamine transporter in rat striatum using [3H]DA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50125905((3R,4S)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...)
Affinity DataIC50: 11.2nMAssay Description:Binding affinity towards dopamine transporter in rat striatum using [3H]WIN-35 428 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed