BDBM50125832 (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid methyl ester::2-Hydroxy-4-oxo-4-phenyl-but-2-enoic acid methyl ester::CHEMBL16633::CHEMBL177429::CHEMBL456227

SMILES COC(=O)C(=O)CC(=O)c1ccccc1

InChI Key InChIKey=AQYAHPDSJAFBOS-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50125832   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50125832(CHEMBL16633 | CHEMBL456227 | CHEMBL177429 | (Z)-2-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against Hepatitis C virus RNA dependent RNA polymerase nonstructural protein 5BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50125832(CHEMBL16633 | CHEMBL456227 | CHEMBL177429 | (Z)-2-...)
Affinity DataIC50: 3.33E+5nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50125832(CHEMBL16633 | CHEMBL456227 | CHEMBL177429 | (Z)-2-...)
Affinity DataIC50: 3.33E+5nMAssay Description:Inhibition of HIV1 integrase 3' processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50125832(CHEMBL16633 | CHEMBL456227 | CHEMBL177429 | (Z)-2-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory concentration against cap-dependent endonuclease activity of influenza virus RNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50125832(CHEMBL16633 | CHEMBL456227 | CHEMBL177429 | (Z)-2-...)
Affinity DataEC50: >2.50E+5nMAssay Description:Plaque growth inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50125832(CHEMBL16633 | CHEMBL456227 | CHEMBL177429 | (Z)-2-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of cap 1 ALMV primed Influenza transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed