BDBM50125801 4-[1-Benzyl-4-(4-chloro-benzyl)-piperidin-4-yl]-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL278402::CHEMBL463590

SMILES OC(=O)C(=O)CC(=O)C1(Cc2ccc(Cl)cc2)CCN(Cc2ccccc2)CC1

InChI Key InChIKey=PTFUDYJJFMXNJA-UHFFFAOYSA-N

Data  1 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50125801   

TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50125801(CHEMBL463590 | CHEMBL278402 | 4-[1-Benzyl-4-(4-chl...)
Affinity DataIC50: 430nMAssay Description:Inhibitory concentration against cap-dependent endonuclease activity of influenza virus RNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50125801(CHEMBL463590 | CHEMBL278402 | 4-[1-Benzyl-4-(4-chl...)
Affinity DataIC50: 350nMAssay Description:Inhibitory concentration against cap-dependent endonuclease activity of influenza A/PR/8/34 RNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50125801(CHEMBL463590 | CHEMBL278402 | 4-[1-Benzyl-4-(4-chl...)
Affinity DataEC50:  860nMAssay Description:Plaque growth inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50125801(CHEMBL463590 | CHEMBL278402 | 4-[1-Benzyl-4-(4-chl...)
Affinity DataIC50: 430nMAssay Description:Inhibition of cap 1 ALMV primed Influenza transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50125801(CHEMBL463590 | CHEMBL278402 | 4-[1-Benzyl-4-(4-chl...)
Affinity DataIC50: 350nMAssay Description:Inhibition of Influenza replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50125801(CHEMBL463590 | CHEMBL278402 | 4-[1-Benzyl-4-(4-chl...)
Affinity DataKi:  90nMAssay Description:Binding affinity to PA N-terminal domain (Competitive)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed