BDBM50125746 1'-[3-(4-methoxyphenyl)-2-(1,2,3,4-tetrahydro-3-isoquinolinylcarboxamido)propanoyl]-1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]::CHEMBL429212

SMILES COc1ccc(C[C@@H](NC(=O)[C@H]2Cc3ccccc3CN2)C(=O)N2CCC3(CN(c4ccccc34)S(C)(=O)=O)CC2)cc1

InChI Key InChIKey=VUBJXOZNUFDRSM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125746   

TargetMelanocortin receptor 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125746(1'-[3-(4-methoxyphenyl)-2-(1,2,3,4-tetrahydro-3-is...)
Affinity DataEC50:  40nMAssay Description:In vitro effective concentration towards human Melanocortin 4 receptor (MC4R) was determined by a SPA-based cAMP assay in melanoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125746(1'-[3-(4-methoxyphenyl)-2-(1,2,3,4-tetrahydro-3-is...)
Affinity DataEC50:  220nMAssay Description:In vitro inhibitory concentration against human Melanocortin 1 receptor (MC1R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed