BDBM50125744 2-Amino-N-[2-(4-butyryl-4-phenyl-piperidin-1-yl)-1-(4-methoxy-benzyl)-2-oxo-ethyl]-3-(1H-imidazol-4-yl)-propionamide::CHEMBL446941

SMILES CCCC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)[C@H](N)Cc1cnc[nH]1)c1ccccc1

InChI Key InChIKey=ZQZZWEILEDVQTR-UHFFFAOYSA-N

Data  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50125744   

TargetMelanocortin receptor 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125744(2-Amino-N-[2-(4-butyryl-4-phenyl-piperidin-1-yl)-1...)
Affinity DataEC50:  1.70E+3nMAssay Description:In vitro effective concentration towards human Melanocortin 3 receptor (MC3R) was determined by a SPA-based cAMP assay in melanoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125744(2-Amino-N-[2-(4-butyryl-4-phenyl-piperidin-1-yl)-1...)
Affinity DataEC50:  1.5nMAssay Description:In vitro effective concentration towards human Melanocortin 1 receptor (MC1R) in SPA-based cAMP assay in melanoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125744(2-Amino-N-[2-(4-butyryl-4-phenyl-piperidin-1-yl)-1...)
Affinity DataIC50: 32nMAssay Description:In vitro inhibitory concentration of the compound against human Melanocortin 1 receptor (MC1R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125744(2-Amino-N-[2-(4-butyryl-4-phenyl-piperidin-1-yl)-1...)
Affinity DataEC50:  630nMAssay Description:In vitro effective concentration towards human Melanocortin 4 receptor (MC4R) was determined by a SPA-based cAMP assay in melanoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125744(2-Amino-N-[2-(4-butyryl-4-phenyl-piperidin-1-yl)-1...)
Affinity DataEC50:  1.00E+4nMAssay Description:In vitro effective concentration towards human Melanocortin 5 receptor (MC5R) was determined by a SPA-based cAMP assay in melanoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed