BDBM50125501 CHEMBL16255::N-[4-(3-Allyl-ureido)-1-phenyl-cyclohexylmethyl]-2-methoxy-benzamide

SMILES COc1ccccc1C(=O)NC[C@]1(CC[C@@H](CC1)NC(=O)NCC=C)c1ccccc1

InChI Key InChIKey=DWUAIAOAUXYSMK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125501   

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125501(N-[4-(3-Allyl-ureido)-1-phenyl-cyclohexylmethyl]-2...)
Affinity DataIC50: 29nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125501(N-[4-(3-Allyl-ureido)-1-phenyl-cyclohexylmethyl]-2...)
Affinity DataIC50: 676nMAssay Description:Inhibition of T-cell proliferation was determined by a human T-cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125501(N-[4-(3-Allyl-ureido)-1-phenyl-cyclohexylmethyl]-2...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed