BDBM50125497 CHEMBL417995::{4-[(2-Methoxy-benzoylamino)-methyl]-4-phenyl-cyclohexyl}-carbamic acid methyl ester

SMILES COC(=O)N[C@H]1CC[C@](CNC(=O)c2ccccc2OC)(CC1)c1ccccc1

InChI Key InChIKey=HBDPGSXHNFQMBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125497   

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125497({4-[(2-Methoxy-benzoylamino)-methyl]-4-phenyl-cycl...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of T-cell proliferation was determined by a human T-cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125497({4-[(2-Methoxy-benzoylamino)-methyl]-4-phenyl-cycl...)
Affinity DataIC50: 135nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed