BDBM50125342 3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-biphenyl-4-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid dimethylamide::CHEMBL12102

SMILES CCCc1nc(CC)c(C(=O)N(C)C)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C

InChI Key InChIKey=FCUQWHAINXOYOX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125342   

TargetType-1 angiotensin II receptor A/B(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125342(3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-biphen...)
Affinity DataKi:  51nMAssay Description:Binding affinity towards Angiotensin II receptor, type 1 in rat aortic smooth muscle cells using 0.2 nM [125I]-labeled Sar-Ile-angiotensin IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125342(3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-biphen...)
Affinity DataKi:  55nMAssay Description:Binding affinity towards human ETA receptor expressed in CHO-K1 cells in the presence of 0.05 nM [125I]-labeled endothelin 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed