BDBM50125002 CHEMBL163437::N-[4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-[2-oxo-4-(4-trifluoromethyl-benzenesulfonyl)-piperazin-1-yl]-acetamide

SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(cc1)C(F)(F)F)C(=O)c1nccs1

InChI Key InChIKey=PZAPLRNNUDVYPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125002   

TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50125002(N-[4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-[2...)
Affinity DataIC50: 10nMAssay Description:In vitro binding affinity towards factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50125002(N-[4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-[2...)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro inhibitory activity against serine protease thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed