BDBM50124940 (2,4-Dimethyl-1-oxy-pyridin-3-yl)-(4'-methyl-[1,4']bipiperidinyl-1'-yl)-methanone::CHEMBL163078

SMILES Cc1cc[n+]([O-])c(C)c1C(=O)N1CCC(C)(CC1)N1CCCCC1

InChI Key InChIKey=KRBMMTDOLHPSPA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50124940   

TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50124940((2,4-Dimethyl-1-oxy-pyridin-3-yl)-(4'-methyl-[1,4'...)
Affinity DataKi:  47.6nMAssay Description:Inhibitory activity against CCR5 receptor in CHO cell membranes was determined using radio-ligand [125I]-RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50124940((2,4-Dimethyl-1-oxy-pyridin-3-yl)-(4'-methyl-[1,4'...)
Affinity DataKi:  93nMAssay Description:Inhibitory activity against CCR5 receptor in CHO cell membranes was determined using radio-ligand [125I]-RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50124940((2,4-Dimethyl-1-oxy-pyridin-3-yl)-(4'-methyl-[1,4'...)
Affinity DataKi:  97.8nMAssay Description:Inhibitory activity against CCR5 receptor in CHO cell membranes was determined using radio-ligand [125I]-RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50124940((2,4-Dimethyl-1-oxy-pyridin-3-yl)-(4'-methyl-[1,4'...)
Affinity DataKi:  98nMAssay Description:Inhibitory activity against CCR5 receptor in CHO cell membranes was determined using radio-ligand [125I]-RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed