BDBM50124925 4-Trifluoromethyl-N-(3-trifluoromethyl-benzyl)-benzamidine::CHEMBL348360

SMILES NC(=NCc1cccc(c1)C(F)(F)F)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=STWLDQPTELSTDF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124925   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124925(4-Trifluoromethyl-N-(3-trifluoromethyl-benzyl)-ben...)
Affinity DataIC50: 660nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124925(4-Trifluoromethyl-N-(3-trifluoromethyl-benzyl)-ben...)
Affinity DataKi:  700nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed