BDBM50124923 CHEMBL162080::N-(3,5-Dimethyl-benzyl)-4-trifluoromethyl-benzamidine

SMILES Cc1cc(C)cc(CN=C(N)c2ccc(cc2)C(F)(F)F)c1

InChI Key InChIKey=MEBWTXIADKMHNS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124923   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124923(N-(3,5-Dimethyl-benzyl)-4-trifluoromethyl-benzamid...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124923(N-(3,5-Dimethyl-benzyl)-4-trifluoromethyl-benzamid...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed