BDBM50124917 CHEMBL349727::N-(3-Methoxy-benzyl)-4-trifluoromethoxy-benzamidine

SMILES COc1cccc(CN=C(N)c2ccc(OC(F)(F)F)cc2)c1

InChI Key InChIKey=IQBVDNRATVHASP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124917   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124917(N-(3-Methoxy-benzyl)-4-trifluoromethoxy-benzamidin...)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124917(N-(3-Methoxy-benzyl)-4-trifluoromethoxy-benzamidin...)
Affinity DataKi:  23nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed