BDBM50124915 CHEMBL161421::N-Benzyl-4-trifluoromethoxy-benzamidine

SMILES NC(=NCc1ccccc1)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=MFYLPPQKSKWOII-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124915   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124915(N-Benzyl-4-trifluoromethoxy-benzamidine | CHEMBL16...)
Affinity DataIC50: 46nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124915(N-Benzyl-4-trifluoromethoxy-benzamidine | CHEMBL16...)
Affinity DataKi:  120nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed