BDBM50124892 (E)-N-Benzyl-3-phenyl-acrylamidine::CHEMBL158874

SMILES N=C(NCc1ccccc1)C=Cc1ccccc1

InChI Key InChIKey=HEXBAJSBFNYKJO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124892   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124892((E)-N-Benzyl-3-phenyl-acrylamidine | CHEMBL158874)
Affinity DataIC50: 70nMAssay Description:Inhibition of the response to glutamate/glycine in NR1a/NR2B expressing cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2014
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124892((E)-N-Benzyl-3-phenyl-acrylamidine | CHEMBL158874)
Affinity DataKi:  9nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124892((E)-N-Benzyl-3-phenyl-acrylamidine | CHEMBL158874)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]ifenprodil binding to recombinant human NR1a/NR2B receptors expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2014
Entry Details Article
PubMed