BDBM50124581 CHEMBL3621529::US20230339856, Compound (IIg)

SMILES OC[C@@]12CCCN1C[C@H](O)[C@@H](O)[C@@H]2O

InChI Key InChIKey=VAJIQEORJZUVIB-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50124581   

TargetBeta-galactosidase(Bovine)
Savitribai Phule Pune University (Formerly University of Pune)

Curated by ChEMBL
LigandPNGBDBM50124581(CHEMBL3621529 | US20230339856, Compound (IIg))
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of bovine liver beta-galactosidase using 10 mM p-nitrophenyl-beta-D-galactopyranoside as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
UniversitÉ

US Patent
LigandPNGBDBM50124581(CHEMBL3621529 | US20230339856, Compound (IIg))
Affinity DataIC50: 460nMAssay Description:The rhGAA enzyme sold under the name Myozyme used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Human)
UniversitÉ

US Patent
LigandPNGBDBM50124581(CHEMBL3621529 | US20230339856, Compound (IIg))
Affinity DataIC50: 3.87E+5nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetBeta-galactosidase(Bovine)
Savitribai Phule Pune University (Formerly University of Pune)

Curated by ChEMBL
LigandPNGBDBM50124581(CHEMBL3621529 | US20230339856, Compound (IIg))
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of bovine liver beta-galactosidase using 10 mM p-nitrophenyl-beta-D-galactopyranoside as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed