BDBM50124575 CHEMBL3623735

SMILES OC(=O)c1ccccc1Nc1cccc(c1)S(F)(F)(F)(F)F

InChI Key InChIKey=AOSAIHVVLGCXQM-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50124575   

TargetAcid-sensing ion channel 5(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50124575(CHEMBL3623735)
Affinity DataEC50:  1.40E+6nMAssay Description:Binding affinity to rat bile acid-sensitive ion channel expressed in xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50124575(CHEMBL3623735)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant AKR1C3 (unknown origin) using S-tetralol as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50124575(CHEMBL3623735)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant AKR1C2 (unknown origin) using S-tetralol as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50124575(CHEMBL3623735)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of COX1 (unknown origin) using arachidonic acid substrate by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50124575(CHEMBL3623735)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of COX2 (unknown origin) using arachidonic acid substrate by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50124575(CHEMBL3623735)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed