BDBM50124564 CHEMBL174088::methyl 3-{4-[2-iodo-(Z)-1-ethenyl]phenyl}-(2S,3S)-8-azabicyclo[3.2.1]octane-2-carboxylate

SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1c1ccc(\C=C/I)cc1)N2

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124564   

TargetSodium-dependent serotonin transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50124564(methyl 3-{4-[2-iodo-(Z)-1-ethenyl]phenyl}-(2S,3S)-...)
Affinity DataKi:  0.0500nMAssay Description:In vitro competitive binding versus [3H]citalopram in murine kidney cells transfected with cDNA for human serotonin transporter (SERT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50124564(methyl 3-{4-[2-iodo-(Z)-1-ethenyl]phenyl}-(2S,3S)-...)
Affinity DataKi:  3.47nMAssay Description:In vitro competitive binding versus [N-methyl-3H]WIN-35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50124564(methyl 3-{4-[2-iodo-(Z)-1-ethenyl]phenyl}-(2S,3S)-...)
Affinity DataKi:  24nMAssay Description:In vitro competitive binding versus [3H]- nisoxatine in murine kidney cells transfected with cDNA for human norepinephrine transporter (NET)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed