BDBM50124481 5-Methyl-pyridine-2-sulfonic acid [2-(2-hydroxymethyl-pyridin-4-yl)-5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-pyrimidin-4-yl]-amide::CHEMBL176963

SMILES COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#C)-c1ccnc(CO)c1

InChI Key InChIKey=WOOHTOSSXGHYSO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124481   

TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124481(5-Methyl-pyridine-2-sulfonic acid [2-(2-hydroxymet...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124481(5-Methyl-pyridine-2-sulfonic acid [2-(2-hydroxymet...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed