BDBM50124460 4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-(4-phenoxy-but-2-ynyloxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide::CHEMBL173689

SMILES COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#CCOc1ccccc1)-c1ncccn1

InChI Key InChIKey=YZCIBWHZHRZYCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124460   

TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124460(4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-(4-phenoxy...)
Affinity DataIC50: 139nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124460(4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-(4-phenoxy...)
Affinity DataIC50: 973nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed