BDBM50124087 CHEMBL101563::N-(1H-Benzoimidazol-5-ylmethyl)-2-(6-methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl)-acetamide

SMILES Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc2nc[nH]c2c1

InChI Key InChIKey=BDCJAGQAAOPKLF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124087   

TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124087(N-(1H-Benzoimidazol-5-ylmethyl)-2-(6-methyl-2-oxo-...)
Affinity DataKi:  11nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124087(N-(1H-Benzoimidazol-5-ylmethyl)-2-(6-methyl-2-oxo-...)
Affinity DataKi:  17nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124087(N-(1H-Benzoimidazol-5-ylmethyl)-2-(6-methyl-2-oxo-...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed