BDBM50124027 6-Hydroxy-4-phenyl-benzo[4,5]furo[2,3-b]pyridine-3-carboxylic acid ethyl ester::CHEMBL132904::ethyl-(6-hydroxy-4-phenylbenzo[4,5]furo[2,3-b])pyridine-3-carboxylate

SMILES CCOC(=O)c1cnc2oc3ccc(O)cc3c2c1-c1ccccc1

InChI Key InChIKey=ZIAVUCXRGWKBBY-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50124027   

LigandPNGBDBM50124027(6-Hydroxy-4-phenyl-benzo[4,5]furo[2,3-b]pyridine-3...)
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 1-cyclin B from M phase starfish (Marthasterias glacialis) oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50124027(6-Hydroxy-4-phenyl-benzo[4,5]furo[2,3-b]pyridine-3...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GST-tagged CDK5/p25 (unknown origin) expressed in Baculovirus infected Sf9 cells using histone H1 as substrate as substrate in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50124027(6-Hydroxy-4-phenyl-benzo[4,5]furo[2,3-b]pyridine-3...)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of His-tagged CDK2/cyclin E (unknown origin) expressed in Baculovirus infected Sf9 cells using histone H1 as substrate in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50124027(6-Hydroxy-4-phenyl-benzo[4,5]furo[2,3-b]pyridine-3...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GST-tagged CDK7/cyclinH/MAT1 (unknown origin) expressed in Baculovirus infected Sf9 cells using YSPTSPS-2 KK peptide as substrate as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50124027(6-Hydroxy-4-phenyl-benzo[4,5]furo[2,3-b]pyridine-3...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of GST-tagged CDK2/cyclin A2 (unknown origin) expressed in Escherichia coli using histone H1 as substrate in presence of [gamma-33P]-ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50124027(6-Hydroxy-4-phenyl-benzo[4,5]furo[2,3-b]pyridine-3...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GST-tagged CDK9/CyclinT1 (unknown origin) expressed in Baculovirus infected Sf9 cells using YSPTSPS-2 KK peptide as substrate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50124027(6-Hydroxy-4-phenyl-benzo[4,5]furo[2,3-b]pyridine-3...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of His-tagged CDK1/cyclin B1 (unknown origin) expressed in Baculovirus infected Sf9 cells using histone H1 as substrate in presence of [ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50124027(6-Hydroxy-4-phenyl-benzo[4,5]furo[2,3-b]pyridine-3...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GST-tagged CDK4/cyclin D1 (unknown origin) expressed in Baculovirus infected Sf9 cells using RPPTLSPIPHIPR peptide as substrate in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed