BDBM50123970 CHEMBL168961::N-Hydroxy-3-[4-(naphthalene-1-sulfonylamino)-phenyl]-acrylamide::US8796330, 93

SMILES ONC(=O)\C=C\c1ccc(NS(=O)(=O)c2cccc3ccccc23)cc1

InChI Key InChIKey=ISHCSRKCMDQJLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123970   

TargetHistone deacetylase 1(Human)
Methylgene

US Patent
LigandPNGBDBM50123970(US8796330, 93 | CHEMBL168961 | N-Hydroxy-3-[4-(nap...)
Affinity DataIC50: 50nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Methylgene

US Patent
LigandPNGBDBM50123970(US8796330, 93 | CHEMBL168961 | N-Hydroxy-3-[4-(nap...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity on partially purified recombinant human Histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed