BDBM50123954 (E)-N-(2-Amino-phenyl)-3-[4-(3,4-dimethoxy-phenylsulfamoyl)-phenyl]-acrylamide::CHEMBL148968::N-(2-Amino-phenyl)-3-[4-(3,4-dimethoxy-phenylsulfamoyl)-phenyl]-acrylamide::US8796330, 118

SMILES COc1ccc(NS(=O)(=O)c2ccc(\C=C\C(=O)Nc3ccccc3N)cc2)cc1OC

InChI Key InChIKey=VHQPTGPWNAFGFE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123954   

TargetHistone deacetylase 1(Human)
Methylgene

US Patent
LigandPNGBDBM50123954(US8796330, 118 | CHEMBL148968 | (E)-N-(2-Amino-phe...)
Affinity DataIC50: 2.30E+3nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Methylgene

US Patent
LigandPNGBDBM50123954(US8796330, 118 | CHEMBL148968 | (E)-N-(2-Amino-phe...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity on partially purified recombinant human Histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

US Patent
LigandPNGBDBM50123954(US8796330, 118 | CHEMBL148968 | (E)-N-(2-Amino-phe...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration against human Histone deacetylase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed