BDBM50123623 (R)-13-(3-aminopyrrolidin-1-yl)-12-fluoro-10-oxo-10H-naphtho[1,2-c]pyrido[3,2,1-kl]phenoxazine-9-carboxylic acid::13-[3-amino-(3R)-tetrahydro-1H-1-pyrrolyl]-12-fluoro-10-oxo-10H-naphtho[1,2-c]pyrido[3,2,1-kl]phenoxazine-9-carboxylic acid::CHEMBL346068

SMILES N[C@@H]1CCN(C1)c1c(F)cc2c3c1oc1c4ccc5ccccc5c4ccc1n3cc(C(O)=O)c2=O

InChI Key InChIKey=ODUKWYWEUZJFKM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123623   

TargetDNA polymerase I, thermostable(Thermus aquaticus)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50123623((R)-13-(3-aminopyrrolidin-1-yl)-12-fluoro-10-oxo-1...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Taq DNA polymerase by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase I, thermostable(Thermus aquaticus)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50123623((R)-13-(3-aminopyrrolidin-1-yl)-12-fluoro-10-oxo-1...)
Affinity DataIC50: 60nMAssay Description:Inhibition of Taq DNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Toulouse

Curated by ChEMBL
LigandPNGBDBM50123623((R)-13-(3-aminopyrrolidin-1-yl)-12-fluoro-10-oxo-1...)
Affinity DataIC50: 60nMAssay Description:Induction of poison effect at DNA topoisomerase 2 by G-quadruplex interaction polymerase stop assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed