BDBM50123469 (3-Benzyl-phenyl)-(8-hydroxy-[1,6]naphthyridin-7-yl)-methanone::(3-benzylphenyl)(8-hydroxy-1,6-naphthyridin-7-yl)methanone::CHEMBL36070

SMILES Oc1c(ncc2cccnc12)C(=O)c1cccc(Cc2ccccc2)c1

InChI Key InChIKey=KOIRVGGHXVYBOP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50123469   

TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123469((3-benzylphenyl)(8-hydroxy-1,6-naphthyridin-7-yl)m...)
Affinity DataIC50: 40nMAssay Description:Compound was tested for its ability to inhibit the strand transfer of the integration process catalyzed by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123469((3-benzylphenyl)(8-hydroxy-1,6-naphthyridin-7-yl)m...)
Affinity DataIC50: 40nMAssay Description:Strand transfer inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123469((3-benzylphenyl)(8-hydroxy-1,6-naphthyridin-7-yl)m...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Cyprus

Curated by ChEMBL
LigandPNGBDBM50123469((3-benzylphenyl)(8-hydroxy-1,6-naphthyridin-7-yl)m...)
Affinity DataIC50: 40nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed