BDBM50123443 (4,6-Dimethyl-pyrimidin-5-yl)-(4-{(S)-4-[(S)-1-(4-iodo-phenyl)-ethyl]-3-methyl-piperazin-1-yl}-4-methyl-piperidin-1-yl)-methanone::CHEMBL422326

SMILES C[C@H](N1CCN(C[C@@H]1C)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C)c1ccc(I)cc1

InChI Key InChIKey=LULHPKFDNFSVFW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123443   

TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123443((4,6-Dimethyl-pyrimidin-5-yl)-(4-{(S)-4-[(S)-1-(4-...)
Affinity DataKi:  11nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123443((4,6-Dimethyl-pyrimidin-5-yl)-(4-{(S)-4-[(S)-1-(4-...)
Affinity DataKi:  169nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed