BDBM50123273 19-cyclopropylmethyl-(2S,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol::19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol::CHEMBL346173

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncccc1C[C@@]35O

InChI Key InChIKey=UUKFYSADJMUSTK-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50123273   

TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123273(19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity for Opioid receptor delta 1 was determined by inhibition of binding of [3H]DADLE (1.3-2.0 nM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123273(19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity to delta opioid receptor was measured using [3H]DADLEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123273(19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity at opioid receptor delta 1 by displacement of [3H]DADLE in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123273(19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for Opioid receptor mu 1 was determined by inhibition of binding of [3H]DAMGO (1.4-3 nM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123273(19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to mu opioid receptor was measured using [3H]DAMGOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123273(19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity at Opioid receptor mu 1 by displacement of [3H]DAMGO in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123273(19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity for kappa opioid receptor was measured using [3H]U-69593More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123273(19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity for Opioid receptor kappa 1 was determined by inhibition of binding of [3H]U-69593 (1.2-2.2 nM) to guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123273(19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity at Opioid receptor kappa 1 by displacement of [3H]U-69593 in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed