BDBM50123205 2-(4-hydroxyphenyl)-1,2'-spirobi[1H-indene]-5-ol::CHEMBL281499

SMILES Oc1ccc(cc1)C1=Cc2cc(O)ccc2C11Cc2ccccc2C1

InChI Key InChIKey=NRJDKQAGGSKGKV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50123205   

TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123205(2-(4-hydroxyphenyl)-1,2'-spirobi[1H-indene]-5-ol |...)
Affinity DataIC50: 4.30nMAssay Description:Binding affinity for Human Estrogen receptor-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123205(2-(4-hydroxyphenyl)-1,2'-spirobi[1H-indene]-5-ol |...)
Affinity DataIC50: 2.10nMAssay Description:Binding affinity for Human Estrogen receptor-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123205(2-(4-hydroxyphenyl)-1,2'-spirobi[1H-indene]-5-ol |...)
Affinity DataIC50: 1.10nMAssay Description:Binding affinity foor Rat Estrogen receptor-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123205(2-(4-hydroxyphenyl)-1,2'-spirobi[1H-indene]-5-ol |...)
Affinity DataIC50: 2.10nMAssay Description:Binding affinity for estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123205(2-(4-hydroxyphenyl)-1,2'-spirobi[1H-indene]-5-ol |...)
Affinity DataIC50: 4.30nMAssay Description:Binding affinity for estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed