BDBM50123064 2-(3-chloro-4-(4-hydroxy-3-(piperidin-1-ylsulfonyl)phenoxy)-5-methylphenyl)-1,2,4-triazine-3,5(2H,4H)-dione::2-{3-Chloro-4-[4-hydroxy-3-(piperidine-1-sulfonyl)-phenoxy]-5-methyl-phenyl}-2H-[1,2,4]triazine-3,5-dione::CHEMBL125728

SMILES Cc1cc(cc(Cl)c1Oc1ccc(O)c(c1)S(=O)(=O)N1CCCCC1)-n1ncc(=O)[nH]c1=O

InChI Key InChIKey=GUAVICDUHINOJD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123064   

TargetThyroid hormone receptor beta(Human)
University of Insubria

Curated by ChEMBL
LigandPNGBDBM50123064(2-{3-Chloro-4-[4-hydroxy-3-(piperidine-1-sulfonyl)...)
Affinity DataIC50: 0.363nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of Insubria

Curated by ChEMBL
LigandPNGBDBM50123064(2-{3-Chloro-4-[4-hydroxy-3-(piperidine-1-sulfonyl)...)
Affinity DataKi:  0.130nMAssay Description:Effective concentration binding towards TR-beta-1 in E25B2 cells (agonistic activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed