BDBM50123051 1-[4-(4-Hydroxy-3-isopropyl-phenoxy)-3,5-dimethyl-phenyl]-tetrahydro-pyrimidin-2-one::CHEMBL124844

SMILES CC(C)c1cc(Oc2c(C)cc(cc2C)N2CCCNC2=O)ccc1O

InChI Key InChIKey=DMSXJMHCVZWNTG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123051   

TargetThyroid hormone receptor beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50123051(1-[4-(4-Hydroxy-3-isopropyl-phenoxy)-3,5-dimethyl-...)
Affinity DataKi:  1.00E+4nMAssay Description:Effective concentration binding towards TR-beta-1 in E25B2 cells (agonistic activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed