BDBM50122841 3-(3H-1lambda*4*-Thiophen-3-yl)-6-thiophen-3-yl-4H-pyrazolo[1,5-a]pyrimidin-7-one::CHEMBL322697

SMILES O=c1c(cnc2c(c[nH]n12)-c1ccsc1)-c1ccsc1

InChI Key InChIKey=RUUQIDHIIXNHBY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50122841   

LigandPNGBDBM50122841(3-(3H-1lambda*4*-Thiophen-3-yl)-6-thiophen-3-yl-4H...)
Affinity DataKi:  23nMAssay Description:Binding affinity for recombinant rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50122841(3-(3H-1lambda*4*-Thiophen-3-yl)-6-thiophen-3-yl-4H...)
Affinity DataKi:  196nMAssay Description:Binding affinity for recombinant rat GABA-A receptor alpha-3-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50122841(3-(3H-1lambda*4*-Thiophen-3-yl)-6-thiophen-3-yl-4H...)
Affinity DataKi:  200nMAssay Description:Binding affinity for recombinant rat GABA-A receptor alpha-2-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50122841(3-(3H-1lambda*4*-Thiophen-3-yl)-6-thiophen-3-yl-4H...)
Affinity DataKi:  223nMAssay Description:Binding affinity for recombinant rat GABA-A receptor alpha-5-beta-3-gamma-2 subunits expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed