BDBM50122764 2-Amino-1-(5-bromo-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidin-4-ylmethyl)-3H-imidazol-1-ium; chloride::5-bromo-6-[(2-aminoimidazol-1-yl)methyl]uracil hydrochloride::CHEMBL122679::CHEMBL65986

SMILES Nc1[nH+]ccn1Cc1[nH]c(=O)[nH]c(=O)c1Br

InChI Key InChIKey=XUBIFQIUVKXXLR-UHFFFAOYSA-O

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50122764   

TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122764(CHEMBL122679 | 2-Amino-1-(5-bromo-2,6-dioxo-1,2,3,...)
Affinity DataIC50: 1.90nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant purified Escherichia coli Thymidine PhosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122764(CHEMBL122679 | 2-Amino-1-(5-bromo-2,6-dioxo-1,2,3,...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122764(CHEMBL122679 | 2-Amino-1-(5-bromo-2,6-dioxo-1,2,3,...)
Affinity DataIC50: 19nMAssay Description:Inhibitory activity against Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetThymidine phosphorylase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122764(CHEMBL122679 | 2-Amino-1-(5-bromo-2,6-dioxo-1,2,3,...)
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration against human thymidine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed