BDBM50122649 (2-Chloro-4-{2-[2-hydroxy-2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenoxy)-acetic acid ethyl ester; hydrochloride::CHEMBL544427

SMILES CCOC(=O)COc1ccc(CCNC(C)C(O)c2ccc(O)cc2)cc1Cl

InChI Key InChIKey=OWJSVNHNFSCPRV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50122649   

TargetBeta-3 adrenergic receptor(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50122649((2-Chloro-4-{2-[2-hydroxy-2-(4-hydroxy-phenyl)-1-m...)
Affinity DataEC50:  7.40nMAssay Description:Concentration required to effect a 50% relaxation of ferret detrusor basal toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Rat)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50122649((2-Chloro-4-{2-[2-hydroxy-2-(4-hydroxy-phenyl)-1-m...)
Affinity DataIC50: 520nMAssay Description:Inhibition of spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Dog)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50122649((2-Chloro-4-{2-[2-hydroxy-2-(4-hydroxy-phenyl)-1-m...)
Affinity DataIC50: 525nMAssay Description:Agonistic activity for Beta-2 adrenergic receptor was assessed by it's inhibitory effect on spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed