BDBM50122530 4-[16,17-dimethyl-13-(1,4-oxazinan-4-yl)-17-azatetracyclo[7.6.2.02,7.010,15]heptadeca-2(7),3,5,12,14-pentaen-4-yl]-1,4-oxazinane

SMILES C[C@@H]1[C@@H]2C3=CC(=CC[C@H]3[C@H](Cc3ccc(cc23)N2CCOCC2)N1C)N1CCOCC1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50122530   

TargetMu-type opioid receptor(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50122530(4-[16,17-dimethyl-13-(1,4-oxazinan-4-yl)-17-azatet...)
Affinity DataIC50: 690nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50122530(4-[16,17-dimethyl-13-(1,4-oxazinan-4-yl)-17-azatet...)
Affinity DataIC50: 7.50E+3nMAssay Description:In vitro binding affinity against cloned human Opioid receptor delta 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50122530(4-[16,17-dimethyl-13-(1,4-oxazinan-4-yl)-17-azatet...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro binding affinity against cloned human Opioid receptor kappa 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed