BDBM50122462 3-{1-[2,5-Dioxo-1-[4-(pyrrolidine-1-carbonyl)-phenyl]-pyrrolidin-(3Z)-ylidene]-ethyl}-benzamidine::CHEMBL321526

SMILES NC(=N)c1cccc(c1)C(=C)c1cc(O)n(c1O)-c1ccc(cc1)C(=O)N1CCCC1

InChI Key InChIKey=BDHHMBDNXOCHNG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50122462   

TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122462(3-{1-[2,5-Dioxo-1-[4-(pyrrolidine-1-carbonyl)-phen...)
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration to coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122462(3-{1-[2,5-Dioxo-1-[4-(pyrrolidine-1-carbonyl)-phen...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory concentration required against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122462(3-{1-[2,5-Dioxo-1-[4-(pyrrolidine-1-carbonyl)-phen...)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibitory concentration required against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed