BDBM50122372 1-(2,6-Dichloro-phenyl)-6-(2,4-difluoro-phenylsulfanyl)-3,4-dihydro-1H-pyrido[3,2-d]pyrimidin-2-one::1-(2,6-dichlorophenyl)-6-(2,4-difluorophenylthio)-3,4-dihydropyrido[3,2-d]pyrimidin-2(1H)-one::CHEMBL92788

SMILES Fc1ccc(Sc2ccc3N(C(=O)NCc3n2)c2c(Cl)cccc2Cl)c(F)c1

InChI Key InChIKey=SBYHQPVTFYWZBH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50122372   

TargetMitogen-activated protein kinase 11(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122372(1-(2,6-dichlorophenyl)-6-(2,4-difluorophenylthio)-...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122372(1-(2,6-dichlorophenyl)-6-(2,4-difluorophenylthio)-...)
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122372(1-(2,6-dichlorophenyl)-6-(2,4-difluorophenylthio)-...)
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122372(1-(2,6-dichlorophenyl)-6-(2,4-difluorophenylthio)-...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122372(1-(2,6-dichlorophenyl)-6-(2,4-difluorophenylthio)-...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122372(1-(2,6-dichlorophenyl)-6-(2,4-difluorophenylthio)-...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed