BDBM50122363 CHEMBL3622439

SMILES CN(C)C(=O)c1cncc(c1)-c1ccc-2c(CCc3nnc(C)n-23)c1

InChI Key InChIKey=LLQSZEPBESZTKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50122363   

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122363(CHEMBL3622439)
Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of human CYP11B1 expressed in V79 cells assessed as cortisol level after 3 hrs by HTRF assay in presence of 250 nM 11-deoxycortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122363(CHEMBL3622439)
Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells assessed as aldosterone level after 3 hrs by HTRF assay in presence of 125 nM 11-deoxycorticostero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed