BDBM50122358 CHEMBL3622431

SMILES C1CC1c1nnc2CCc3cc(ccc3-n12)-c1cccnc1

InChI Key InChIKey=RTWDTXKWUNXISB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50122358   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122358(CHEMBL3622431)
Affinity DataIC50: 487nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells assessed as aldosterone level after 3 hrs by HTRF assay in presence of 125 nM 11-deoxycorticostero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122358(CHEMBL3622431)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP11B1 expressed in V79 cells assessed as cortisol level after 3 hrs by HTRF assay in presence of 250 nM 11-deoxycortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed