BDBM50122348 (2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropyl]-3-methyl-hexa-2,4-dienoic acid::CHEMBL89581

SMILES C\C(\C=C\CC1(CC1)c1cc(cc(c1)C(C)(C)C)C(C)(C)C)=C/C(O)=O

InChI Key InChIKey=BGVPDBYBQCFFGN-UHFFFAOYSA-N

Data  6 Kd  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50122348   

TargetRetinoic acid receptor alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122348((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Affinity DataEC50:  733nMAssay Description:Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122348((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Affinity DataEC50:  139nMAssay Description:Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122348((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Affinity DataKd:  3nMAssay Description:Transcriptional activation in CV-1 cells expressing human Retinoid X receptor RXR-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122348((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Affinity DataEC50:  391nMAssay Description:Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-gamma(Mouse)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122348((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Affinity DataEC50:  23nMAssay Description:Transcriptional activation in CV-1 cells expressing mouse Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122348((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Affinity DataKd:  16nMAssay Description:Inhibition of [3H]-9-cis-RA binding to human Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Mouse)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122348((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Affinity DataKd:  8nMAssay Description:Inhibition of [3H]9-cis-RA binding to mouse Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122348((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Affinity DataEC50:  30nMAssay Description:Transcriptional activation in CV-1 cells expressing human Retinoid X receptor RXR-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122348((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Affinity DataKd: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to human Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122348((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Affinity DataKd: >1.00E+3nMAssay Description:Inhibition of [3H]ATRA binding to human Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122348((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Affinity DataKd: >1.00E+3nMAssay Description:Inhibition of [3H]ATRA binding to human Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Mouse)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122348((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Affinity DataEC50:  19nMAssay Description:Transcriptional activation in CV-1 cells expressing mouse Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed