BDBM50122309 ((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydroxy-4-phenyl-butyl)-phosphonic acid::CHEMBL310981

SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CC(F)(F)P(O)(O)=O)[C@H](O)c1ccccc1

InChI Key InChIKey=KQPGDBVGEXAZAW-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50122309   

TargetSphingomyelin phosphodiesterase 2(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase [1-45,48-631](Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibitory activity against Acid sphingomyelinase from bovine brain microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against schyphostatin of neutral sphingomyelinase (N-SMase) from bovine brain microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed