BDBM50121912 CHEMBL282602::[(S)-1-((3S,4S)-2-Oxo-4-phenoxy-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester

SMILES O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@H]1[C@@H](NC1=O)Oc1ccccc1)OCc1ccccc1

InChI Key InChIKey=NGAUZCRIRRLFOO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50121912   

TargetCathepsin S(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121912([(S)-1-((3S,4S)-2-Oxo-4-phenoxy-azetidin-3-ylcarba...)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Rat)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121912([(S)-1-((3S,4S)-2-Oxo-4-phenoxy-azetidin-3-ylcarba...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of recombinant rat Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121912([(S)-1-((3S,4S)-2-Oxo-4-phenoxy-azetidin-3-ylcarba...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121912([(S)-1-((3S,4S)-2-Oxo-4-phenoxy-azetidin-3-ylcarba...)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human Cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121912([(S)-1-((3S,4S)-2-Oxo-4-phenoxy-azetidin-3-ylcarba...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human Cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed