BDBM50121910 CHEMBL30969::[(S)-1-((2S,3S)-2-Butoxy-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester

SMILES CCCCO[C@@H]1NC(=O)[C@H]1NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=GFBNAICZWORTRP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50121910   

TargetCathepsin K(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121910([(S)-1-((2S,3S)-2-Butoxy-4-oxo-azetidin-3-ylcarbam...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human Cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Rat)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121910([(S)-1-((2S,3S)-2-Butoxy-4-oxo-azetidin-3-ylcarbam...)
Affinity DataIC50: 7.01E+3nMAssay Description:Inhibition of recombinant rat Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121910([(S)-1-((2S,3S)-2-Butoxy-4-oxo-azetidin-3-ylcarbam...)
Affinity DataIC50: 355nMAssay Description:Inhibition of recombinant human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121910([(S)-1-((2S,3S)-2-Butoxy-4-oxo-azetidin-3-ylcarbam...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121910([(S)-1-((2S,3S)-2-Butoxy-4-oxo-azetidin-3-ylcarbam...)
Affinity DataIC50: 163nMAssay Description:Inhibition of recombinant human Cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed