BDBM50121903 CHEMBL31272::[(S)-1-((3R,4R)-2-Oxo-4-phenylsulfanyl-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester

SMILES O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@H]1[C@H](NC1=O)Sc1ccccc1)OCc1ccccc1

InChI Key InChIKey=LKVLCOTZWXWKQV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50121903   

TargetCathepsin K(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121903([(S)-1-((3R,4R)-2-Oxo-4-phenylsulfanyl-azetidin-3-...)
Affinity DataIC50: 72nMAssay Description:Inhibition of recombinant human Cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121903([(S)-1-((3R,4R)-2-Oxo-4-phenylsulfanyl-azetidin-3-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121903([(S)-1-((3R,4R)-2-Oxo-4-phenylsulfanyl-azetidin-3-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human Cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Rat)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121903([(S)-1-((3R,4R)-2-Oxo-4-phenylsulfanyl-azetidin-3-...)
Affinity DataIC50: 3.97E+4nMAssay Description:Inhibition of recombinant rat Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121903([(S)-1-((3R,4R)-2-Oxo-4-phenylsulfanyl-azetidin-3-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed